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Ghrelin in Bariatric Surgery

Pathophysiological role of plasma ghrelin in weight loss after laparoscopic bariatric procedures.

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Ghrelin connects stomach and brain; secreted mainly by stomach fundus, acts on the hypothalamus stimulating appetite. Plasma levels are inversely related to BMI and nutritional status and show a sharp post-meal decrease. Bariatric surgery achieves weight loss in most of patients mainly reducing the volume of the stomach.

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